ISSN 2757-8135 | E-ISSN 2757-9816
Analysis of patients undergoing amniotic membrane transplantation at a tertiary referral hospital [Eur Eye Res]
Eur Eye Res. 2021; 1(2): 64-68 | DOI: 10.14744/eer.2021.04706

Analysis of patients undergoing amniotic membrane transplantation at a tertiary referral hospital

Mine Karahan1, Atılım Armağan Demirtaş2, Seyfettin Erdem1, Sedat Ava1, Leyla Hazar1, Mehmet Emin Dursun1, Yasin Çınar1, Uğur Keklikçi1
1Department of Ophthalmology, Dicle University Faculty of Medicine, Diyarbakir, Turkey
2Department of Ophthalmology, Health Scienes University, Izmir Tepecik Training and Research Hospital, Izmir, Turkey

PURPOSE: In this study, we aimed to determine amniotic membrane transplantation (AMT) indications, early results and demographic analysis of patients who underwent AMT in our clinic according to age and gender.
METHODS: The records of 154 patients who underwent AMT at the Ophthalmology Clinic between April 2017 and September 2019 were reviewed retrospectively. Examination findings and demographic data of the patients were examined and recorded. Patients were divided into five groups: 0–10 years (Group 1, n=7), 11–20 years (Group 2, n=9), 21–40 years (Group 3, n=23), 41–60 years (Group 4, n=32), and over 60 years (60–89 years) (Group 5, n=83).
RESULTS: Ninety-five (61.7%) of the patients included in the study were male and 59 (38.3%) were female. The mean age of the patients was 55.72±22.53 (Range: 0–89) years. The most common indications for AMT in all age groups were corneal ulcer (n=47, 30.5%), corneal melting (n=32, 20.8%), and persistent epithelial defect (PED) (n=21, 13.6%). The most common age groups for AMT were Group 5 (n=83, 53.9%), Group 4 (n=32, 20.8%), and Group 3 (n=23, 14.9%). The most common indications for AMT in children and adolescents (0–20 years) were corneal ulcer (n=6, 37.5%) and corneal chemical burns (n=5, 31.2%), while in adults over 21 years of age, AMT indications were corneal ulcer (n=41, 29.7%) and corneal melting (n=29, 21.0%).

CONCLUSION: The most common indications for AMT in our study were corneal ulcer, corneal melting, and PED. According to the indications, AMT may be a simple and easily applicable surgical method that can be used in the reconstruction of the ocular surface in many corneal and conjunctival pathologies.

Keywords: Amniotic membrane, corneal ulcer, ocular surface reconstruction.

Mine Karahan, Atılım Armağan Demirtaş, Seyfettin Erdem, Sedat Ava, Leyla Hazar, Mehmet Emin Dursun, Yasin Çınar, Uğur Keklikçi. Analysis of patients undergoing amniotic membrane transplantation at a tertiary referral hospital. Eur Eye Res. 2021; 1(2): 64-68

Corresponding Author: Atılım Armağan Demirtaş, Türkiye