Ocular toxoplasmosis is the most common cause of infectious retinochoroiditis in humans. Atypical and unilateral presentations as papillitis without vitritis are especially challenging for diagnosis. Here, we report a case of 17-year-old man with a unilateral toxoplasma papillitis without vitritis. Fundus examination revealed unilateral inflammation in the right optic disc and peripapillary area. Toxoplasma Ig M titer was positive and IgG negative. During the follow up, while the IgM titer decreased, the IgG titer increased. After possible etiologies excluded, the patient was diagnosed presumed Toxoplasma papillitis with complete absence of vitritis at presentation. The patient treated with appropriate antiparasitic agents and good response observed without recurrence.
Keywords: Ocular toxoplasmosis, papillitis, Toxoplasma Ig M