ISSN 2757-8135 | E-ISSN 2757-9816
European Eye Research
Assessment of C-reactive protein to albumin ratio in patients with retinal vein occlusion [Eur Eye Res]
Eur Eye Res. Ahead of Print: EER-14622 | DOI: 10.14744/eer.2021.14622

Assessment of C-reactive protein to albumin ratio in patients with retinal vein occlusion

Işıl Kutlutürk Karagöz1, Muhammed Nurullah Bulut2
1Department of Ophthalmology, University of Health Sciences Umraniye Training and Research Hospital, Istanbul, Turkey
2Department of Ophthalmology, Kartal Dr. Lutfi Kirdar City Hospital, Istanbul, Turkey

PURPOSE: The relationship between retinal vein occlusion (RVO) and hematologic parameters has been previously demon-strated. However, there is lacking data regarding the role of C-reactive protein (CRP) to Albumin Ratio (CAR) in patients with RVO. In this study, we aimed to investigate the relationship between CAR and RVO.
METHODS: A total of 126 people were included in our study, including 63 patients diagnosed with central RVO (CRVO) in our hospital and 63 control patients. All clinical, demographical, and laboratory parameters were entered into a dataset and compared between the CRVO group and the controls.
RESULTS: The mean age of the patients was 54±11 years (Female: 47.6%). CRP and CAR were significantly higher in patients with CRVO compared to controls (p<0.001, p<0.001, respectively). Logistic regression analysis demonstrated that high CAR level was an independent determinant of CRVO (Odds Ratio: 3.300, 95% Confidence interval: 1.681–6.480; p=0.001).
CONCLUSION: Higher CAR levels may be an associated predictor of CRVO.

Keywords: C-reactive protein to albumin ratio, inflammation; retinal vein occlusion.



Corresponding Author: Işıl Kutlutürk Karagöz, Türkiye
Manuscript Language: English