Assessment of C-reactive protein to albumin ratio in patients with retinal vein occlusion

PURPOSE: The relationship between retinal vein occlusion (RVO) and hematologic parameters has been previously demonstrated. However, there is lacking data regarding the role of C-reactive protein (CRP) to Albumin Ratio (CAR) in patients with RVO. In this study, we aimed to investigate the relationship between CAR and RVO.
METHODS: A total of 126 people were included in our study, including 63 patients diagnosed with central RVO (CRVO) in our hospital and 63 control patients. All clinical, demographical, and laboratory parameters were entered into a dataset and compared between the CRVO group and the controls.
RESULTS: The mean age of the patients was 54±11 years (Female: 47.6%). CRP and CAR were significantly higher in patients with CRVO compared to controls (p<0.001, p<0.001, respectively). Logistic regression analysis demonstrated that high CAR level was an independent determinant of CRVO (Odds Ratio: 3.300, 95% Confidence interval: 1.681–6.480; p=0.001).
CONCLUSION: Higher CAR levels may be an associated predictor of CRVO.