Cataract surgery has some difficulties in nanophthalmic eyes, it may be possible to overcome these complications with some precautions. In the present study we share the application of a phacoemulsification and pars plana anterior vitrectomy for the treatment of dense cataract and an iridozonulohyaloidectomy to counter the risk of malignant glaucoma in a patient with nanophthalmos following intraocular pressure regulation by micropulse transscleral diode laser cyclophotocoagulation. The intraocular pressure of our patient became normal, his visual acuity increased significantly in the postoperative period, and no complications were observed.